Job Description

Company Description

Bicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (previously BT8009), a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle Radio Conjugates (BRC(TM)) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.


Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, Massachusetts.

Culture

is key and all Bicycle employees actively embrace and role model our company values:

We are

Adventurous

. We believe it's the way to deliver extraordinary results for our patients. We are

Dedicated to our Mission

. You can't change the world if you don't have determination. We are

One Team

. We only succeed when we work together.

Role purpose

As our company expands, we have created an exciting new opportunity for a 1st / 2nd Line IT Support Engineer to join our UK team at Granta Park near Cambridge.


You will support the IT systems throughout the organisation. These include setup and maintenance of desktop computers, our server environment, as well as maintain our cyber security posture. You will work with a variety of teams, based in the UK and US, and look to maintain the excellent IT standards currently practiced at Bicycle.

Key responsibilities

Help support the Corporate IT Team at Bicycle, comprising all general day to day support activities. Support an internal helpdesk and triage tickets, escalating as necessary. Assist with IT project work whether on-site or in cloud. Work across departments to deliver IT-driven solutions to empower scientific R&D. Work with enterprise security, DR and data solutions to ensure business continuity. Providing routine desktop support to all staff, including the Microsoft Office suite, SharePoint online, Microsoft Teams and Windows 10/11 operating systems. Setting up hardware and software for new staff, being responsible for on and off boarding staff. Supporting and troubleshooting networking equipment and issues, including wireless. Working closely with the IT Team Leader to meet corporate IT goals and continue developing and strengthening our cyber security posture. Work with existing Manager Service Provider's in UK and US. Help manage current server environments.

This is a hybrid-based role, with the expectations of at least

3 days onsite

.

We are recruiting for a Fixed Term Contract (FTC) until the end of 2025.

Qualifications

Essential

Demonstrable experience with: + Office365
+ SharePoint
+ Windows
+ PowerShell
+ AzureAD + SSO
+ Active Directory
+ MDM platforms
+ Enterprise-grade networking
+ Firewalls (Paolo Alto)
+ SSL+IPSEC VPNs
+ Enterprise-grade backup systems
Extensive Windows desktop/server support experience. Experience with enterprise-grade security platforms. Some experience of Linux/Unix systems and administration. An eye for detail

Desirable

Experience of project delivery. Experience working under lab conditions. Experience with: + AWS
+ GCP
+ Azure Cloud Platform
+ Long term data storage
+ Veeva
Experience of working in the life sciences. Awareness of Cybersecurity standards and best practices.

Additional Information

State-of-the-art campus environment with on campus restaurant and Montessori nursery Flexible working environment Competitive reward including annual company bonus Employee recognition schemes 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually Employer contribution to pension (employee does not have to contribute) Life assurance cover 4x basic salary Private Medical Insurance, including optical and dental cover. Group income protection Employee assistance program Health Cash Plan Access to company subsidized gym membership. Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc. Cycle to work scheme
Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.