Job Description

We are seeking an experienced scientist to oversee the delivery of a range of established in vitro genetic toxicology screening assays. Supporting our customers from start to finish, you will be responsible for all aspects of planning, scheduling, testing and reporting of data from these key screening assays.

About us

Gentronix is located at Alderley Park in the north-west UK and is part of the wider Scantox Group of companies. Across Scantox Group and the Gentronix site, we are committed to helping our clients develop safer chemicals and medicines, using innovative screening platforms as well as GLP regulatory tests to detect hazard, to understand mode-of-action, and help manage risk.

Comprising a team of over 65 employees with a range of experiences from within the pharmaceutical, agrochemical and CRO industries, our team has extensive expertise in the field of genetic and predictive toxicology. Together with our colleagues in Scantox Group, ambition is to become the leading provider of predictive and preclinical toxicology products and services across a variety of industry sectors.

The benefits

Company Pension Scheme 8% company contribution 25 days holiday plus Bank Holidays Private Medical Insurance Life assurance x2 salary Employee Assistance Programme (EAP) Retail discounts Mental Health Wellbeing platforms Financial Wellbeing Enhanced Maternity, Paternity, Shared Parental and Adoption leave policy
Gentronix has a collaborative and supportive culture with plenty of opportunities for you to grow and succeed. We offer excellent training, personal development opportunities and routes for career progression across all our teams.

Your role

With a focus on customer service, you will ensure genetic toxicology screening data is delivered to deadline and offer support to our customers with data interpretation and follow-up testing strategies. In conjunction with other senior team members, you will take responsibility for the smooth running of the laboratory, troubleshooting, validation of new instrumentation and provide training and mentoring to more junior team members. This role will require you to be hands-on in the laboratory, contributing to regular cell-based assay testing as well as working on improvement projects.

Specifically, you will:

Manage screening assays within the laboratory, serving as the primary contact for any laboratory-related issues or troubleshooting and ensuring efficient and optimal workflows. Lead non-GLP screening studies in accordance with documented procedures and address technical issues to minimise disruptions. Act as a Responsible Scientist on screening studies and be the scientific contact for clients Offer expertise on non-standard testing, provide regular updates on study progress, and provide advice to customers on effective screening strategies. Analyse data, verify data accuracy and quality, draw sound scientific conclusions and generate suitable reports. Manage multiple studies concurrently, adhering to timelines and deliverables. Ensure all documentation is complete, accurate and compliant with requirements. Collaborate across teams to deliver studies or projects that deliver exceptional value to the business and/or customers. Provide leadership to more junior scientists, offering guidance, mentorship and training on experimental techniques, data analysis and best practices. Lead relevant new assay development and instrument validation projects. Take responsibility for instrumentation within the laboratory, acting as the expert user and working closely with the Facilities Team to ensure instruments and equipment are maintained in a validated and ready state.

About you

To join us as an Associate Principal Scientist I in our Screening Team, you will need:

Bachelors degree in life sciences (or equivalent qualification); advanced degree preferred.

Sufficient hands-on experience of working in a life science laboratory to confidently lead a commercial screening services offering. Experience of high-throughput cell-based assays, cell culture and maintenance and genetic toxicology endpoints. Strong hands-on experience of flow cytometry and sound understanding of this technique. Ideally experience of delivering screening services in a contract research setting, including managing customer relationships. Demonstrated ability to work both independently and collaboratively in a team environment. Strong scientific communication skills, with the ability to deliver and explain experimental results and interpretation in verbal and written forms. Advanced IT skills, including proficiency in Microsoft Office and laboratory data management systems. Ideally, experience of introducing new technologies. Other organisations may call this role Responsible Scientist or Study Director.
Gentronix are an equal opportunities employer, and we value diversity and are strongly committed to providing equal employment opportunities for all employees and all applications for employment. Equal opportunities are the only acceptable way to conduct business and we believe that the more inclusive our environments are, the better our work will be.

Job Types: Full-time, Permanent

Benefits:

Bereavement leave Company pension Employee discount Enhanced maternity leave Enhanced paternity leave Free flu jabs Free parking Health & wellbeing programme On-site parking Private medical insurance Referral programme Sick pay
Ability to commute/relocate:

Macclesfield SK10: reliably commute or plan to relocate before starting work (required)
Experience:

study directing: 1 year (required)
Work authorisation:

United Kingdom (required)
Work Location: In person