Job Description

The Role

To help drive therapeutics discovery and characterisation we are seeking a bioinformatician to join our team in Edinburgh. This is a hybrid role, but the candidate should be based in (or prepared to move to) Edinburgh.


The successful candidate will create novel pipelines to analyse single cell and spatial transcriptomic data, and help construct our internal databases. They will be working closely with the Bioinformatics team to deliver these goals and to help build the target discovery platform. This role will provide opportunities to collaborate extensively with our colleagues based at our Cambridge R&D site.

Responsibilities

Run single-cell and single-nuclei RNA-seq analytical pipelines and assess outputs to identify further therapeutic targets as part of our discovery platform Work with fellow Bioinformaticians to establish spatial transcriptomic analysis pipelines to identify novel therapeutic targets Maintain an up-to-date knowledge in single cell genomics analytical methodologies Work collaboratively with the Forth Therapeutics scientific team and with external research groups and partners Communicate effectively, interpret and summarise data for presentation to different audiences Maintain accurate and up-to-date electronic records and code repository Work closely with the scientific team to help build the drug discovery platform and pipeline

Experience and Requirements

Essential

A PhD or Masters in a relevant scientific discipline (or industry equivalent experience) Understanding of single cell transcriptome and/or genome data analysis. Understanding, experience and/or published outcomes from analysing and interpreting large datasets. Experience in using statistical (e.g. R) and/or programming (e.g. Python, Java) languages. Strong statistical and analytical skills. Excellent written and spoken English, and the ability to communicate effectively both within the team and with collaborators in the UK and worldwide. Good interpersonal skills and efficient time management skills. An ability to work independently, developing, running and trouble-shooting new scientific techniques and experimental protocol An ambition to work with the Forth Therapeutics team to build a transformative company

Desirable

Direct experience of 10x Genomics Chromium single cell or single nuclei transcriptomics data analysis Direct experience of 10x Genomics Xenium or VisiumHD spatial transcriptomics data analysis Experience in pipeline construction and implementation with Nextflow A desire to learn more about machine learning applications in bioinformatics




NOTE:

This job description is not intended to be all inclusive. Employees may perform other related duties as negotiated to meet the ongoing needs of the organisation.

Note to recruitment agencies: we are not looking for assistance at this stage so please contact the HR department only at hr@forthtx.com if you think you can help in the future.