Job Description

Electrophysiologist

Background

Autifony is a cutting-edge biotech company dedicated to developing new medicines to treat CNS disorders by deploying its pioneering ion channel drug discovery platform. Since its formation in 2011, Autifony has delivered multiple candidate molecules into clinical development. The Company's clinical pipeline includes Kv3 modulators for Schizophrenia, Fragile X and rare epilepsy syndromes. Autifony's early-stage pipeline contains a range of ligand- and voltage-gated channels, including a particular interest in lysosomal targets, that are aligned with CNS indications such as epilepsy, neurodegeneration (Parkinson's, Alzheimer's disease), vascular dementia and lysosomal storage disorders.

Autifony is based at the Stevenage Bioscience Catalyst in the UK (www.autifony.com).

Requirement

Looking to expand its biology team, Autifony is seeking a highly motivated electrophysiologist with experience in ion channel research and pharmacology/drug discovery to become part of a dynamic preclinical R&D group focused on the discovery and development of novel ion channel therapeutics.

This is a one-year contract.

Experience

The applicant should have relevant hands-on experience and a demonstrable track record in in vitro whole cell patch-clamp recordings (or similar) from recombinant, native and/or tissue slices within the pharma, biotech, and/or CRO life sciences sector. Candidates should have a good understanding of ion channels, neuroscience and the principles of electrophysiology and pharmacology. Candidates with experience of lysosomal biology (including lysopatch), compound mechanism of action studies and/or the use of automated platforms (e.g. PatchlinerTM or SURFE2RTM) are encouraged to apply

Responsibilities

Planning, designing, conducting, troubleshooting and analysing bespoke experiments aligned with the drug discovery and new target validation goals of the company The candidate will be expected to prepare experimental summaries, presentations at internal and external meetings e.g. at project teams or with partners companies or at conferences, and prepare research reports and contribute to research papers for publication

Essential Skills

Applicants must have good written and oral communication skills in English. Highly motivated to learn and/or apply new techniques to the field of ion channel drug discovery Ability to work independently and as part of a team

Qualifications

PhD degree preferred. Additional experience including postdoc or equivalent industry experience in biological will also be considered.

APPLICATION PROCESS:

For full consideration, please send a cover letter containing information regarding your research interests and a CV, to: info@autifony.com

Job Types: Full-time, Fixed term contract
Contract length: 12 months

Additional pay:

Yearly bonus
Benefits:

Company pension On-site parking Private medical insurance
Schedule:

Day shift Monday to Friday
Work authorisation:

United Kingdom (required)
Work Location: In person