Job Description

Company Description:
Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.
Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions:
Consistently Ranked Science's Top Employer
Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we've been named the No. 1 company to work for in the biopharma industry in Science's Top Employers survey for four years in a row.
A Certified Great Place to Work
We believe our company is truly special, and our employees agree. In July 2025, we became Great Place to Work-certified in the U.S. for the fifth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma(TM), Best Workplaces in New York(TM), PEOPLE Companies That Care, Best Workplaces for Women(TM), Best Workplaces for Millennials(TM), and Best Medium Workplaces(TM) lists.
Summary: This is an outstanding opportunity for an experienced in vivo Scientist to join the Insmed Innovation in vivo team and work closely with cross-functional teams situated in Babraham Cambridge. Utilizing your in-depth knowledge, you will develop a vision on how the in vivo team can support all aspects of early target identification, target validation and drug discovery programs. You will enjoy the fast pace of a growing biotech and thrive in a collaborative, passionate, multidisciplinary team with the mission of validating proprietary targets and contributing to drug discovery programs. Responsibilities:

• Work with program leads and senior leadership team on overall in vivo project plans.
• Use your expertise to support the design, implementation, and evaluation of in vivo studies (both in house as well as with CROs) to enable target identification, target validation and drug discovery across different projects.
• Plan and execute lab-based work followed by review and analysis of endpoint data including characterization of mouse models (both via image and behavior methods), efficacy studies and small scale PK/PD studies, etc.
• Prepare study reports, summaries and regulatory documents.
• Lead continuous improvement activities, applying problem solving skills to identify workflow efficiencies and implement technology solutions to enhance processes.
• Work with internal stakeholders to ensure learning is captured and incorporated into processes and practices.
• Actively contribute to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared among the teams.
• Work collaboratively with Bioinformatics and Human Genetics teams to gain an integrated biological understanding of target biology and its role in disease.
• Scientific coaching and mentorship of colleagues in our matrix-based team.

What we are looking for:

• 5 years plus experience in a relevant scientific discipline working with in vivo models with both in-house & external partners. Expertise working in a neurodegenerative disease area would be advantageous. We will also consider Scientist I level experience for this opportunity.
• UK Home Office Licence holder with proven in vivo experience and experimental skills working with animal models.
• Experience with mouse model characterization such as behavior phenotyping and/or image-based analysis.
• Experience in planning and execution of efficacy studies, ideally with expertise in complex dosing routes such as IT, ICV, ICM and placement of cannulation for repeat dosing in mouse.
• Expertise in tissue collection ideally for CNS related studies (e.g spinal cord, different brain regions) and sample processing (e.g fixation/embedding for histology) would be advantageous.
• In-depth understanding of requirements around regulated procedures and Home Office licence requirements, providing welfare advice and support for ongoing projects.
• Experienced at managing complex external collaborations and partnerships to successfully achieve project goals.
• Attention to detail, excellent analytical skills and an understanding of statistical methods, preparation of reports, summaries, electronic database entries and regulatory documents.

Compensation & Benefits:
At Insmed, we're committed to investing in every team member's total well-being, now and in the future. Our benefit programs vary by country but we offer the following to all Insmed team members, regardless of geographic location:

• Flexible approach to how we work
• Comprehensive health insurance and time-off plans
• Competitive compensation package, including bonus
• Equity Awards (Long-Term Incentives)
• Employee Stock Purchase Plan (ESPP)

Additional Information:
Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.
Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.
Applications will close on 26th September 2025

Skills Required