The Lung Cancer Prevention Laboratory, run by Dr Deborah Caswell is situated within UCL Respiratory, a department within the Division of Medicine at UCL. UCL Respiratory has a comprehensive laboratory suite. The laboratory includes tissue culture facilities for experimental work with cancer cell lines, and the recently refurbished department also included a comprehensive histology facility and microscope suite. Our laboratory through a collaboration with Professor Janes laboratory, has access to samples from two unparalleled studies, SUMMIT and ASCENT (samples from 13000 participants with a high risk of lung cancer and 500 patients with lung cancers). Our laboratory also has access to unique preclinical models including novel humanized lung cancer mouse models with APOBEC3 gene expression, as well as a large panel of transplantable EGFR mutant mouse lung cancer cell lines, and human lung cancer cell lines. These are cutting edge models that are not available anywhere else in the world.
About the role
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In this post the successful candidate will delineate the DNA damage induced by APOBEC3 enzymes in human and mouse lung cancer cell line models. Overall the candidate is expected to plan and conduct high-quality research ensuring the delivery of key project milestones with the aim to write and publish high quality research. This post is funded for 1 year, and the successful candidate will be based in the UCL Respiratory Department. This role is not suitable for UCL sponsorship.
About you
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The successful applicant will have evidence of carrying out independent research at a high level, strong working knowledge of mammalian cell culture and proficiency in molecular biology techniques including bacterial transformation, protein expression, and purification. The extensive list of essential and desirable criteria is outlined within job description and person specification attached to this advert.
What we offer
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This is an exciting opportunity to join a multidisciplinary team working across the Division of Medicine. As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below: o 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) o Additional 5 days' annual leave purchase scheme o Defined benefit career average revalued earnings pension scheme (CARE) o Cycle to work scheme and season ticket loan o Immigration loan o Relocation scheme for certain posts o On-Site nursery o On-site gym o Enhanced maternity, paternity and adoption pay o Employee assistance programme: Staff Support Service o Discounted medical insurance Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.
Our commitment to Equality, Diversity and Inclusion
As London's Global University, we knowdiversity fosters creativity and innovation, and we want our community torepresent the diversity of the world's talent. We are committed to equality ofopportunity, to being fair and inclusive, and to being a place where we allbelong. We therefore particularly encourageapplications from candidates who are likely to be underrepresented in UCL'sworkforce. These include people from Black, Asian andethnic minority backgrounds; disabled people; LGBTQI+ people Our department holds an Athena SWAN Silveraward, in recognition of our commitment and demonstrable impact in advancinggender equality.
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