Job Description

GSK Barnard Castle is a key secondary manufacturing site and has invested heavily in industry 4.0 state of the art, bespoke equipment to support sustained new product introductions and volume increases, and as a key supplier of some of GSK's blockbuster products, the site contributes revenues of ~$2Bn annually.


We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.


We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.


Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

The successful candidate will provide end-to-end technical ownership for assigned commercial products manufactured at site. Act as the primary point of contact for product and process knowledge, ensuring robust Product Lifecycle Management (PLM) across Product Control Strategy (PCS), Technical Risk Assessment (TRA), Continued Process Verification (CPV) and Process Performance Qualification (PPQ). Drive product performance, compliance and continuous improvement in partnership with Operations, Quality, Engineering and Global MSAT (e.g., Molecule Stewards) to deliver safe, compliant and efficient supply.

This includes two permanent roles across Biologics, Inhalations and Devices and an additional fixed-term contract (FTC) within the Derms team, with shortlisting based on candidate experience.

In this role you will...

Single point of accountability for assigned product(s): maintain and curate comprehensive knowledge of the product, process, CQAs/CPPs/MPPs, historical performance and critical learnings; share knowledge on site and with global partners as appropriate. Product Lifecycle Management: ensure local delivery of the Technical Lifecycle Plan (TLCP) owned by Molecule Stewards; maintain and continuously improve Product Control Strategy, Technical Risk Assessment, and Continued Process Verification. Performance monitoring & data analytics: proactively monitor product/process performance via CPV and site digital platforms where available; identify trends, lead data-driven problem solving and escalate risks with clear mitigation plans (e.g., CAPAs, governance boards). Change impact assessment & compliance: lead product impact assessments for changes (materials, process, equipment, methods, regulatory); ensure robust risk management and compliant execution through change control and validation lifecycle; support inspections, PPRs, dossier updates and audit readiness. Technical leadership: provide product expertise to deviations, complaints and investigations; lead/coach structured RCA and formal problem solving (e.g., FMEA, DMAIC) to prevent recurrence and improve robustness. New product introduction & transfers: provide technical input to NPIs and transfers (to/from site); ensure QbD-based processes, knowledge transfer and right-first-time PPQ; secure effective handover to Operations. Continuous improvement: identify and deliver improvement opportunities for yield, scrap, throughput and sustainability; sponsor and prioritize CI aligned to value-stream strategies. Collaboration & governance: partner with Global MSAT Molecule Stewards, Standards SMEs (e.g., PLM/CPV & Validation), Technical Execution teams, Quality and Production; contribute to product/technical forums (e.g., PTLTs) to align strategy and share best practices.

Why you?

Basic Qualifications & Skills:


BSc in Scientific or Engineering discipline or equivalent experience (e.g., Pharmaceutical Sciences, Chemical/Process Engineering or related). Substantial experience in pharmaceutical manufacturing or MSAT/Technical Operations with a track record of product/process improvement, investigations and successful validation/transfer execution.
Preferred Qualifications & Skills:


Detailed knowledge of relevant dosage form, plant equipment and analytical testing. Awareness of device/packaging processes. Level 1 Facilitator for TRAs ('Proficient' level as defined by the TRA competency framework) Knowledge of regulatory environment, particularly in markets where product is commercialised. Track record of improving Able to evaluate potential innovative technology areas relevant to product Thorough knowledge of GMP and EHS requirements Demonstrated in-depth knowledge of Quality by Design and risk management approaches Able to assess/interpret statistical data e.g. process capability, control charts, DoE, MSA Demonstrates ability to contribute to and effectively influence matrix teams, colleagues in other functions and senior stakeholders Demonstrated ability to mentor operational staff and support functions

Closing Date for Applications: 10th October (COB)

Please take a copy of the , as this will not be available post closure of the advert.


When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.


People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.


GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.


We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.


Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.


Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

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