Job Description

Postdoctoral Research Scientist

Department of Physiology, Anatomy & Genetics, [Domingos group, Sherrington Building, Parks Road]

Contract & job type: Fixed-term (24 months), full-time

About us:

At the Department of Physiology Anatomy & Genetics (DPAG) we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organization. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the role:

We are seeking a postdoc to join the Domingos Group. The ideal candidate will be hold, or be close to completion of a PhD/DPhil in Genomics, Molecular Genetics, Neuroscience, Immunology or equivalent with relevant experience in the generation of single cell sequencing data and analysis. In this role, you will be responsible for testing hypotheses and analysing scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. Develop ideas within the scope of the laboratory, generate data and research income in the form of grant applications, and present detailed research proposals to senior researchers. Develop ideas within the scope of the laboratory, generate data and research income in the form of grant applications. This post is available from 01/01/2025 for 24 months.

Key responsibilities:

Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines

Adapt existing and develop new scientific techniques and experimental protocols

Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate

Contribute ideas for new research projects within the scope of the laboratory

Develop ideas within the scope of the laboratory, generate data and research income in the form of grant applications, and present detailed research proposals to senior researchers

Collaborate in the preparation of grants, scientific reports and journal articles and occasionally present papers and posters

Use specialist scientific equipment in a laboratory environment

Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques

Represent the research group at external meetings/seminars, either with other members of the group or alone

Carry out collaborative projects with colleagues in partner institutions, and research groups

Selection criteria:

Essential selection criteria

Hold, or be close to completion of, a PhD/DPhil in Genomics, or Molecular Genetics, Neuroscience, Immunology or equivalent, together with relevant experience in the generation of single cell sequencing data and analysis

Previous publications related to single cell sequencing analysis and mouse genetics

Previous experience in programming in Python, and/or application of machine learning for analysing data

High level of autonomy and ability to manage own academic research and associated activities

Previous experience of contributing to publications/presentations

Ability to contribute ideas for new research projects and research income generation

Excellent communication skills, including the ability to write for grants and publications, present research proposals and results, and represent the research group at meetings

Previous record of teaching and supervision of students

Commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work

Desirable

Holder of a personal home office licence PIL (A,B) for mouse experimentation.

Experience in molecular biology, cloning, tissue culture, qPCR, ELISA, tissue/cell staining, mouse handling, electrophysiology, calcium imaging.

Commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work.

What we offer:

Your wellbeing at work matters, so we offer a range of family friendly and financial benefits including:
Hybrid working

An excellent contributory pension scheme

38 days annual leave

A comprehensive range of childcare services

Family leave schemes

Cycle and electric car loan schemes

Employee Assistance Programme

Membership to a variety of social and sports clubs

Discounted bus travel and Season Ticket travel loans


While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

How to apply:

Please provide a supporting statement outlining how you meet the selection criteria along with your CV, and the details of two referees as part of your online application.
The closing date for applications is 12 noon on 28/11/2025.
Interviews are likely to take place during the week commencing 15/12/2025.
Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

Follow us:

Stay connected with us on LinkedIn, Bluesky and Instagram to learn more about our work and culture. Informal enquiries about the role may be directed to the DPAG HR Team: hr@dpag.ox.ac.uk

DPAG's Statement of Inclusion:

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. Our policies, practices and Respectful Behaviours Framework underpin this commitment.

DPAG and Sustainability

We have signed up to The Laboratory Efficiency Assessment Framework (LEAF) and Green Impact, actively implementing and encouraging eco-friendly practices that reduce waste, promote energy efficiency, and promote bio-diversity. See the job description for more detail.