Job Description

Job number

MED05325

Faculties

Faculty of Medicine

Departments

Department of Surgery & Cancer

Salary or Salary range

48,056 - 56,345 per annum

Location/campus

Hammersmith Campus - Hybrid

Contract type work pattern

Full time - Fixed term

Posting End Date

20 Jul 2025

About the role

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We are seeking a motivated and experienced biological researcher to work on an exciting Wellcome Trust funded project to investigate how changes in glucagon receptor signalling affect fuel metabolism.



With rates of obesity, steatotic liver disease and type 2 diabetes at an all-time high, we aim to use discovery science to understand the role of dysregulated glucagon signalling in the pathogenesis of these conditions.

What you would be doing

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You will develop protocols for the investigation of glucagon signalling in immortalised cell lines, primary hepatocytes, liver organoids and mice. You will manipulate disease-status using specialised diets and genetic manipulation (CRISPR; AAVs). You will work within a wide-reaching multidisciplinary team of researchers to integrate in-silico modelling, high throughput pharmacological screening and structural characterisation data in developing your research plans.

What we are looking for

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PhD in relevant biological science. Hands-on experience with mouse models for research. Practical experience in cell and tissue culture. Enthusiasm for teaching and supervision Project management and interpersonal skills, with the ability to organise own work with minimal supervision and work collaboratively.

What we can offer you

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The opportunity to continue your career at a world-leading institution and be part of our mission to use science for humanity. Benefit from a sector-leading salary and remuneration package (including 39 days' annual leave and generous pension schemes). Access to a range of workplace benefits including generous family leave packages, on-site leisure facilities and cycle-to-work scheme. Interest-free season ticket loan schemes for travel. Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing.

Further information

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This is a full-time post for 24 months and is available for a start-date from September 2025 based at Hammersmith Campus (East Acton).



Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant.



If you require any further details about the role, please contact: Emma Rose McGlone (e.mcglone@ic.ac.uk)

Available documents

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Attached documents are available under links. Clicking a document link will initialize its download.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

We reserve the right to close the advert prior to the closing date stated should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment.



If you encounter any technical issues while applying online, please don't hesitate to email us at support.jobs@imperial.ac.uk. We're here to help.


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About Imperial

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.



Join us and be part of something bigger. From global health to climate change, AI to business leadership, here at Imperial we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact.



As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network.



This is your chance to help shape the future. We hope you'll join us at Imperial College London.


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Our Culture

We work towards equality of opportunity, to eliminating discrimination, and to creating an inclusive working environment for all. We encourage applications from all backgrounds, communities and industries, and are committed to employing a team that has diverse skills, experiences and abilities. You can read more about our commitment on our webpages.



Our values are at the root of everything we do and everyone in our community is expected to demonstrate respect, collaboration, excellence, integrity, and innovation.