Job Description

Job number

MED05345

Faculties

Faculty of Medicine

Departments

Department of Surgery & Cancer

Salary or Salary range

48,056 - 56,345 per annum

Location/campus

Hammersmith Campus - On site only

Contract type work pattern

Full time - Fixed term

Posting End Date

30 Jul 2025

About the role

------------------


We are seeking to appoint an experienced Postdoctoral Research Associate to join our dynamic multidisciplinary team delivering the National Prostate Cancer Bio-Digital Twin. The Twin will support TRANSFORM Discovery, the translational part of the national prostate screening study TRANSFORM, funded by PCUK and NIHR in partnership with other key funding stakeholders. Our over-arching aim is to capture digital data & process biospecimen from the trial for (i) biomarker testing at scale and pace, (ii) translational & discovery science and (iii) the simulation of in silico trials to inform clinical care. The study plans to recruit up to 300,000 men and to capture associated digital and biological measures that will support cutting edge studies that will transform outcomes for men with prostate cancer across the world.



This is an unprecedented opportunity for an ambitious and dynamic post-doctoral researcher to initiate and develop an independent molecular biology/translational research project using data within TRANSFORM. The post-holder will directly contribute to the establishment, development and delivery TRANSFORM Discovery whilst growing an independent programme under senior mentorship. This opportunity will allow development of new studies spanning discovery, translational and clinical biology towards the development of new treatments, diagnostics and technologies, that benefit patients and communities affected by prostate cancer across the UK and internationally.

What you would be doing

---------------------------


You will help undertake and oversee the day-to-day sample processing for tissue types (e.g. bloods, urine, microbiome, prostate tissue) into molecular components (DNA, RNA, protein) and oversee data-generation (e.g. high through-put multi-omic sequencing), implementing governance frameworks and auditing to ensure the translational work is conducted to the highest scientific and regulatory standards.



You will deliver and publish a whole genome sequencing project, developing analytic pipeline and identify germline characteristics that determine prostate cancer risk. You will be expected to develop additional streams of research relating to translational prostate cancer biology and seek additional external funding.

What we are looking for

---------------------------


You must have post-doctoral level research laboratory experience in cell and molecular biology and demonstrable experience in contemporary high throughput molecular biology methods, including sequencing (e.g. DNA, methylation, transcriptomics) proteomics, metabolomics and microscopy. You must have a high impact publication record (including first author).

What we can offer you

-------------------------


The opportunity to continue your career at a world-leading institution and be part of our mission to use science for humanity. Benefit from a sector-leading salary and remuneration package (including 39 days' annual leave and generous pension schemes). Access to a range of workplace benefits including a flexible working policy from day one, generous family leave packages, on-site leisure facilities and cycle-to-work scheme. Interest-free season ticket loan schemes for travel. Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing.

Further information

-----------------------


This is a full-time fixed term position available with a start date in September 2025.



Appointments will usually be made at the start of the salary scale dependent on experience.



For informal enquiries please contact Professor Rakesh Heer (r.heer@imperial.ac.uk)

Available documents

-----------------------


Attached documents are available under links. Clicking a document link will initialize its download.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

We reserve the right to close the advert prior to the closing date stated should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment.



If you encounter any technical issues while applying online, please don't hesitate to email us at support.jobs@imperial.ac.uk. We're here to help.

About Imperial

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.



Join us and be part of something bigger. From global health to climate change, AI to business leadership, here at Imperial we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact.



As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network.



This is your chance to help shape the future. We hope you'll join us at Imperial College London.

Our Culture

We work towards equality of opportunity, to eliminating discrimination, and to creating an inclusive working environment for all. We encourage applications from all backgrounds, communities and industries, and are committed to employing a team that has diverse skills, experiences and abilities. You can read more about our commitment on our webpages.



Our values are at the root of everything we do and everyone in our community is expected to demonstrate respect, collaboration, excellence, integrity, and innovation.