Job Description

Job number

NAT01982

Faculties

Faculty of Natural Sciences

Departments

Department of Life Sciences

Salary or Salary range

48,056 - 49,895 per annum

Location/campus

South Kensington Campus - On site only

Contract type work pattern

Full time - Fixed term

Posting End Date

22 Jul 2025

About the role

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The Beeby laboratory (https://profiles.imperial.ac.uk/m.beeby) in the Department of Life Sciences (https://www.imperial.ac.uk/life-sciences) would like to recruit a Research Associate with expertise in cryo-electron microscopy. This post, funded by the Medical Research Council, aims to understand the mechanisms underlying how bacterial flagella rotate. The objectives are to determine both in situ and ex situ structures of flagellar motors trapped in clockwise and counterclockwise rotational directions. You will join an exciting interdisciplinary team of structural biologists and microbiologists to tackle this important fundamental question. The project focuses on cryo-electron microscopy (cryo-EM) studies and computational image processing, and will also involve support of other lab members in cryo-EM and image processing.



We are excellently equipped for structural EM work. Cryo-EM facilities host Glacios 200kV XFEG cryo-EM with Falcon 4 and Selectris energy filter, Vitrobot Mk. IV, GPU- and data storage-cluster and ready access to Titan Krioses at the Francis Crick Institute, LonCEN consortium, and the UK national cryoEM facility at eBIC.

What you would be doing

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Duties include:


Manage the running of the project To take initiative in planning and executing of research, and develop collaborations Design and execute appropriate experiments Acquire electron cryo-microscopy data toward understanding bacterial flagellar rotation Process and analyse acquired data Work with lab members to design appropriate mutant bacterial strains to test hypotheses Manage and mentor small teams of more junior colleagues and support learning Be proficient in new approaches and techniques, and integrate these approaches into your research projects.

What we are looking for

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You will have a PhD (or equivalent) in structural biology, ideally with experience in cryo-electron microscopy. You must have a strong research track record in studying protein complexes demonstrated by publications in international journals. Experience in the design and execution of workflow for structure determination of proteins or cellular systems from sample preparation to acquisition and analysis of structural biology data.



You must have excellent communication skills, and be able to write clearly and succinctly for publication. You must also be able to relate well with others, form positive relationships with a wide range of people and to work as part of a team, as well as independently. The ability to develop and apply new concepts and have a creative approach to problem-solving, to set and attain research objectives in a multidisciplinary team are also essential.

What we can offer you

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The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity. Grow your career: Gain access to Imperial's sector-leading dedicated career support for researchers as well as opportunities for promotion and progression Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).

Further information

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This is a full-time, fixed-term appointment available for up to 36 months.


Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant.



If you require any further details on the role please contact: Dr Morgan Beeby m.beeby@imperial.ac.uk

Available documents

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Attached documents are available under links. Clicking a document link will initialize its download.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

We reserve the right to close the advert prior to the closing date stated should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment.



If you encounter any technical issues while applying online, please don't hesitate to email us at support.jobs@imperial.ac.uk. We're here to help.


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About Imperial

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.



Join us and be part of something bigger. From global health to climate change, AI to business leadership, here at Imperial we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact.



As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network.



This is your chance to help shape the future. We hope you'll join us at Imperial College London.


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