Job Description

Job id: 073171. Salary: \xc2\xa342,405 - \xc2\xa353,994 per annum, including London Weighting Allowance.

Posted: 15 August 2023. Closing date: 05 September 2023.

Business unit: Faculty of Life Sciences & Medicine. Department: Randall Cell & Molecular Biophysics.

Contact details: Professor Mathias Gautel. mathias.gautel@kcl.ac.uk

Location: Guy\'s Campus. Category: Research.

Job description

We are seeking a high-quality Grade 6, Post-doctoral Research Associate to contribute to the research undertaken by the Gautel group. The Gautel group, which sits within the Randall Centre for Cell & Molecular Biophysics Department at King\'s, is committed to elucidating the mechanisms that organise sarcomeres and exploring the pathological implications of mutations in sarcomere proteins such as Titin. Further details may be found here Gautel Group

This post will provide research support for the *\xe2\x80\x9c*StuDy SARCOMERE\xe2\x80\x9d project funded by the European Research Council (ERC) and will be carried out in the Gautel group of the Randall Centre of Cell and Molecular Biophysics in collaboration with the partner labs in Europe (Marseille, Dortmund, G\xc3\xb6ttingen). The post holder will use a combination of molecular and cell biology, biochemistry, and advanced imaging techniques in zebrafish and in cells to understand the mechanisms and dynamics of muscle sarcomeric organisation. The successful candidate will have (or be about to complete) a PhD in biochemistry, molecular biology, cell biology or similar and have strong experience with imaging, zebrafish, muscle development, biochemistry, molecular biology, and cell biology. The role may also involve liaising with medical professionals upon investigation of new disease-linked genetic variants, disseminating the research effectively and contributing to further research funding.

Randall Centre for Cell & Molecular Biophysics Department

The Randall department is highly rated in research activities and has an extensive portfolio of taught and research programmes. Supporting our staff is very important to us and we offer a range of provision including flexible working, wellbeing days, caring support, training, and promotion opportunities. Find out more about staff benefits at King\'s here.

This post will be offered on a fixed term contract until 31/01/2026.

This is a full-time post - 100% full time equivalent

Key responsibilities

• Plan and carry out experimental work, devise strategies for further development and advancement of the project.
• Meticulously record, analyse, and write up the results of experiments. Be able to support all scientific conclusions drawn by appropriate record and note keeping.
• Prepare data for inclusion in manuscripts and grant applications.
• Contribute to writing of publications for appropriate scientific journals.
• Attend and present obtained results in posters and/or oral presentations at laboratory meetings, workshops, and conferences.
• Work in collaboration with colleagues as well as other groups, within the UK and abroad, as required by the project.
• Balance the competing pressures of research and administrative demands.
• Conduct research in an ethical and accurate manner.
• Keep up with technical and experimental developments in the field and apply knowledge to experimental interpretations.
• Cooperate and share expertise with all members of the research team.
• Be committed to your own personal career development.
• Be aware of the risks in the work environment and their potential impact on your own work and that of others.
• Undertake any other reasonable duties that may be relevant to the role outline.

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Essential criteria

1. PhD in biochemistry, cell or molecular biology or a related discipline

2. Background in one of the following: biochemistry, cell or molecular biology

3. Background in imaging techniques

4. A good level of computer literacy

5. Good interpersonal skills

6. First Author publication(s)/ Track record of high-quality publications

7. Experience of presenting work to others, e.g. at lab meetings and conferences

8. Managing an independent research project

Desirable criteria

1. Background of working with the zebrafish model

2. Experience in genome editing techniques

3. Background in muscle biology

4. Experience in supporting research students and/or research staff.

5. Ability to communicate conceptual and complex ideas to a variety of audiences using appropriate media and methods.

Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Further information

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible

King\'s College London