Job Description

Position Details

Department of Cancer and Genomic Sciences, School of Medical Sciences, College of Medicine and Health


Location: University of Birmingham, Edgbaston, Birmingham UK


Full time starting salary is normally in the range 36,130 to 45,413 with potential progression once in post to 48,149


Grade: 7


Full Time, Fixed Term contract up to September 2028


Closing date: 21st July 2025

Background

To create and contribute to the creation of knowledge by undertaking a specified range of activities within an established research programme and/or specific research project.

Role Summary

A 3 year Bone Cancer Research Trist/GOSH funded Research Fellow post, starting October, is available within the lab of Prof. Clare Davies and Dr. Susanne Gatz investigating synthetic lethal genetic events with PRMT5 inhibitors in Ewing sarcoma, focusing on the DNA damage response and splicing.


We require a highly motivated and organised individual that is willing to meet deadlines. Principal methodologies include cell culture, analysis of DNA damage and repair by microscopy and RNA-sequencing for splicing analysis.

Main Duties

The responsibilities may include some but not all of the responsibilities outlined below.


Develop research objectives and proposals for own or joint research, with assistance of a mentor if required Analyse and interpret data Apply knowledge in a way which develops new intellectual understanding Disseminate research findings for publication, research seminars etc Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline Contribute to developing new models, techniques and methods Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader Deal with problems that may affect the achievement of research objectives and deadlines Promotes equality and values diversity acting as a role model and fostering an inclusive working culture.

Person Specification

First degree in area of specialism and a PhD (or near to completion) relevant to research area or equivalent qualifications Practical experience of: + Mammalian cell culture, including single molecule DNA fiber analysis
+ Microscopy-based laboratory techniques (including immunofluorescence)
+ Western blotting and immunoprecipitation
+ Analysis of big datasets (e.g. RNA-sequencing)
The ability to work and think independently and to significantly contribute to the planning of a programme of scientific research Effective organisational skills and the ability to prioritise work to meet deadlines Evidence of an ability to work individually and in a research team The ability and willingness to keep up with and have a working knowledge of the scientific literature in the field of the project High level analytical capability Ability to communicate complex information clearly Willingness to work flexibly and out-of-hours when necessary, to fulfil the needs of the research project Co-ordinate own work with others to avoid conflict or duplication of effort Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly.

Informal enquiries to Clare Davies, email: c.c.davies@bham.ac.uk

We believe there is no such thing as a 'typical' member of University of Birmingham staff and that diversity in its many forms is a strength that underpins the exchange of ideas, innovation and debate at the heart of University life. We are committed to proactively addressing the barriers experienced by some groups in our community and are proud to hold Athena SWAN, Race Equality Charter and Disability Confident accreditations. We have an Equality Diversity and Inclusion Centre that focuses on continuously improving the University as a fair and inclusive place to work where everyone has the opportunity to succeed. We are also committed to sustainability, which is a key part of our strategy. You can find out more about our work to create a fairer university for everyone

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