The Kessaris lab is embedded within the Wolfson Institute for Biomedical Research, a leading centre for translational neuroscience within the Division of Medicine at UCL. Our research explores the development of the mammalian forebrain, with a particular focus on how human genetic mutations impact development, brain function and behaviour and contribute to neurodevelopmental disorders. Our well-established team is located within an open-plan state-of-the-art laboratory space with excellent infrastructure and a vibrant collaborative environment. You can find out more about our work here https://profiles.ucl.ac.uk/10296-nicoletta-kessaris/publications.
About the role
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The post is suitable for a highly motivated and dynamic research associate with a strong interest in developmental neuroscience. The project is funded by the UK BBSRC and aims to investigate the role of the autism-associated gene RUNX1T1 in shaping brain development. The project employs a multifaceted approach combining genetically modified models, transcriptomics, as well as in silico and in vivo analysis of protein-protein interactions to elucidate the role of RUNX1T1 in forebrain development. You will be responsible for planning and carrying out the project in consultation with Prof Kessaris and in line with the BBSRC proposal. This is a full-time appointment for a period of two and a half years from the start date and is available immediately. The role offers networking and collaboration opportunities within UCL and leading international collaborators. You will have the opportunity to lead your research projects and attend national and international conferences. Salary: G7, Spine Point 31 (41,103 per annum, inclusive of London Allowance).
About you
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You must have a PhD (or be studying towards it) in a relevant neuroscience discipline and have a strong interest in understanding brain development. The ideal candidate will have a deep understanding of the research background, coupled with the ability to communicate their research achievements effectively to peers. Proficiency in one or more of the following research techniques is essential: transgenic mouse breeding and tissue preparation, DNA/RNA handling, PCR, quantitative RT-PCR, immunofluorescence, mRNA in situ hybridization, confocal microscopy, tissue clearing and lightsheet microscopy, bulk and single cell RNA sequencing, CUT&TAG, ATAC-seq, proximity ligation, CRISPR, protein analysis and co-immunoprecipitation. The ability to analyse and write up data, present complex information effectively to a range of audiences and effective written and verbal communication skills are essential. A track record of collaborative research and supervision of undergraduate and master's project students are desirable.
What we offer
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This is an exciting opportunity to join a multidisciplinary team working across the Division of Medicine. We also offer some great benefits some of which are below: o 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) o Additional 5 days' annual leave purchase scheme o Defined benefit career average revalued earnings pension scheme (CARE) o Cycle to work scheme and season ticket loan o Immigration loan o Relocation scheme for certain posts o On-Site nursery o On-site gym o Enhanced maternity, paternity and adoption pay o Employee assistance programme: Staff Support Service o Discounted medical insurance Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.
Our commitment to Equality, Diversity and Inclusion
As London's Global University, we know diversity fosterscreativity and innovation, and we want our community to represent the diversityof the world's talent. We are committed to equality of opportunity, to beingfair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications fromcandidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minoritybackgrounds; disabled people; LGBTQI+ people Our department holds an Athena SWAN Silver award, inrecognition of our commitment and demonstrable impact in advancing genderequality.
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