Job Description

About us
The RNA Regulation Laboratory, headed by Prof Andres Ramos is a highly dynamic research environment that applies a multi-disciplinary approach to address key questions in RNA Biology and neuronal regulation. The laboratory is part of the Biosciences Division, a centre of research excellence and one of the largest Divisions within UCL.
About the role
The role is focussed on the investigation of the structural and molecular basis of protein-RNA recognition and regulation in neuronal development. Important questions include, but are not limited to, how RNA binding proteins recognise and remodel functionally related mRNAs targets, and how the system is regulated during neuronal development and in response to signalling.
The role holder will be expected to pursue original, multi-disciplinary research. The project entails the application of cryoEM and complementary biophysical methods to study the structure and conformational rearrangement of protein-RNA complexes and will require adaptation of current cryoEM methods to the study of protein-RNA complexes. Notably, the post holder will interface with collaborators and will be an active member of the Ramos lab.

• This is a fixed-term role for 30 months from the time of appointment, in the first instance.
• Research Fellows - 'Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B (salary 38,607- 41,255 per annum) per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD Thesis.'

• This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit

for more information.

• This appointment is subject to UCL Terms and Conditions of Service for Academic Staff. Please visit

for more information.
A job description and person specification can be accessed at the bottom of this page.
If you have any queries about the role, please contact Andres Ramos at
If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact Biosciences staffing at .
About you
The successful applicant should have obtained a PhD in Structural Biology incorporating Cryo-EM methods, and have knowledge of protein expression and purification.
Experience in other biophysical and structural methods would be beneficial. You will be expected to work as part of a tightly integrated team to produce original contributions to the mechanistic understanding of the role of RNA regulators in neuronal development.
Your studies will focus on the understanding of the IGFBP1/IMP1 system, in the first instance. In addition to developing and conducting the research, you will contribute expertise to the overall research effort in the Ramos group. You will also communicate results through scientific publications in leading journals, and as scientific presentations at national and international conferences.
What we offer
As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:
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Our commitment to Equality, Diversity and Inclusion
You can read more about our commitment to Equality, Diversity and Inclusion here:
Customer advert reference: B02-08899