Job Description

Overview:

Certara Predictive Technologies is part of Certara, a company which combines sophisticated research and development informatics with the power of predictive science methodologies to span the drug development spectrum and offer pharma a previously unavailable 'end-to-end' solution in the quest for improving human health. The PBPK team conducts cutting-edge research and provides consultancy, knowledge integration tools, algorithms, modelling solutions and databases (implemented in its globally-recognised Simcyp Population-based Simulator) for a client base of major blue-chip pharmaceutical and biotechnology organisations. This role will be in the Translational DMPK Science team whose focus is on gathering information required for the modelling and simulation (M&S) of the individual time-course and fate of drugs. We are on course to become the global industry standard, consequently, there is a continuous requirement for high quality people to join us, help in our expansion and share in our success.

We have an immediate opening for a Research Scientist with a background in the areas of pharmaceutical sciences to assist with the expansion of physiologically based pharmacokinetic (PBPK) models and compounds and populations libraries within the Simcyp Simulator. The candidate should have experience of in vitro-in vivo extrapolation techniques and an understanding of drug pharmacokinetics.
The candidate should have experience of conducting literature searches and have the ability to critically review literature and conduct meta-analysis of collected physiological, biological and clinical data. The post holder will be expected to assist with on-going customer support, education, and training related to the use of the Simcyp Simulator and to act as tutor on the workshop programmes.
The successful candidate will join an internationally recognised, multidisciplinary research team, providing opportunities for further development of knowledge and skills. The post does not include routine laboratory or clinical work. We offer a unique and exciting mix of academic and commercial environments which encourage regular attendance at scientific meetings as part of our continuous education programs.
Responsibilities:

Active involvement in research and development of PBPK/PD models implemented within the Simcyp Simulators including collating, reviewing and analysing healthy and disease populations as well as compound and clinical data. Preparing implementation documents and developing case studies under guidance or independently leading wish-list and/or strategic projects as needed. Contributing to consultancy projects when required. Applying your experience/expertise in assisting with development and enhancement of module for modelling and simulation of various organs and tissues. Flexibility to learn and work on projects in areas outside of your previous experience e.g., absorption modules when required. Training up to act as a tutor for Simcyp workshops when and if needed. Take on a substantial role in testing the Simulators before and after the release. Disseminating the outcome of research as poster/podium presentations and scientific publications. Communicating with clients and dealing with clients' queries. Taking part in clients' site visits and on-site education. Assisting with the research and development of externally funded projects e.g., grants. Maintaining an active interest and awareness of new research and technologies relevant to the field, expanding your field expertise, and disseminating these within the team



Qualifications:

Essential

MSc with 5 years experience or PhD with 3 years experience or a BSc with 6 years experience. Demonstrable communication skills, as evident by presentation at scientific meetings, and good interpersonal and organizational skills. Track record of publications in peer-reviewed literature.

Desirable

Knowledge of in vitro assays used in drug metabolism, transport, and pharmacokinetic studies and their application in IVIVE approaches. Hands on experience in Physiologically Based Pharmacokinetics modelling and simulation Awareness of R&D process in pharmaceutical companies
Certara bases all employment-related decision on merit, taking into consideration qualifications, skills, achievement, and performance. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.