Job Description

About the Company

Oxford StemTech is a dynamic and innovation-driven biotechnology company with expertise in cellular reprogramming and induced pluripotent stem cell (iPSC) technologies for neuroscience drug discovery.

We are seeking a motivated candidate for the

Scientist

position

,

responsible for in vitro neuronal disease modelling, with emphasis on iPSC-derived trigeminal peptidergic nociceptors. This is a two- year position with a three-month probationary period, with the possibility of extension. The candidate will work closely with and report directly to the Chief Scientific Officer and the Director.

Duties and Key Responsibilities

-

Lead efforts on the iPSC-derived Trigeminal Peptidergic Nociceptor Project: Prioritise and execute research activities focused on disease modelling and target validation relevant to client and internal research objectives.

- iPSC Differentiation: Direct differentiation of human iPSCs into disease-relevant neuronal subtypes for use in neuroscience drug discovery.

- Drug Discovery Assays: Develop and perform assays, assessing the efficacy and mechanism of action of candidate compounds - specific emphasis on Multi-Electrode array (MEA), ELISA, and Calcium imaging.

- Data Analysis: Analyse, interpret, and present experimental results with scientific rigour and clarity.

- Collaborative Research: Work collaboratively with cross-functional research teams on additional scientific projects, supporting the broader mission of the company.

- Scientific Engagement: Stay up to date with scientific developments in iPSC differentiation, neurobiology, and drug discovery, integrating relevant findings into research strategy.

Required qualifications and experience

-

Master's with > 4 year work experience or PhD in Neuroscience or related field.

- Proven expertise in iPSC differentiation protocols to generate neurons, as well as in vitro disease modelling techniques.

- Strong background in neuronal functional assays such as electrophysiology, calcium imaging, live-cell imaging, ELISAs.

- Proficient in cellular and molecular biology techniques, including immunostaining, qPCR, flow cytometry.

- Proficient in data analysis using relevant software and statistical tools.

- Excellent communication skills and ability to work collaboratively in a research team.

Desired Skills

Prior experience working in an industry setting

Experience in complex in vitro models of iPSC-based functional assays

Demonstrated experience working with multi-electrode array platform

Published research findings in peer-reviewed journals is a plus

Experience with gene transfection, CRISPR assays and stable cell line generation

Excellent organisational and project management skills

Remuneration and Benefits

Salary: 38,000 - 43,000 p.a., based on experience

Pension Benefits

Application enquiries should be sent to galbha.duggal@oxfordstemtech.com

Applications from recruitment agencies will not be accepted.

Application deadline is 30th September 2025.

Oxford StemTech Ltd

The Oxford Science Park

Hayakawa Building

Edmund Halley Road

OX4 4GB, United Kingdom

www.OxfordStemTech.com

Job Types: Full-time, Fixed term contract
Contract length: 24 months

Pay: 38,000.00-43,000.00 per year

Benefits:

Company pension On-site parking
Ability to commute/relocate:

Oxford OX4 4GB: reliably commute or plan to relocate before starting work (required)
Application question(s):

Do you have experience working with iPSCs and lineage-specific differentiation?
Work authorisation:

United Kingdom (required)
Work Location: In person