Job Description

Ref Number

B02-09624

Professional Expertise

Research and Research Support

Department

School of Life & Medical Sciences (B02)

Location

London

Working Pattern

Full time

Salary

54,931-64,644

Contract Type

Fixed-term

Working Type

Hybrid

Available for Secondment

No

Closing Date

03-Nov-2025

About us

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The mission of the UCL GOS Institute of Child Health is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children's health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH's activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education and training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

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Applications are invited for a Senior Clinical Project Manager to join the Molecular and Cellular Immunology (MCI) Section at UCL Great Ormond Street Institute of Child Health (UCL GOS ICH). The appointment will be for 12-months initially and may be extended We wish to employ a translational Senior Clinical Project Manager with experience of managing first in human trials and other translational projects & collaborations. It will provide an opportunity to work with cutting edge clinical researchers and interact across inter-disciplinary groups. The gene and cell therapy group are involved in a portfolio of trials involving childhood diseases. You will work with a translational research team with particular responsibility for CAR T cell clinical trials and development of the next generation gene editing. This will include set-up and management of early phase clinical trials for cellular immunotherapies (CAR T trials) and inherited bone marrow conditions. The role will involve writing/reviewing essential documents, preparing & submitting approvals/amendments to MHRA, ethics committees and R&D offices. You will also be responsible for writing progress and safety reports, and wider clinical outputs. You will ensure trials are conducted in line with t protocols, GCP and relevant legislation. Translational studies and laboratory development work will be supported through operational oversight including management of compliance and quality aspects.

About you

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Applicants must have a bachelor's degree in science and previous extensive experience in clinical trials management, including preparation and submission of MHRA/ethics applications and amendments. Expertise in Gene and cell therapy, molecular biology or immunology, is desirable but not essential but the candidate must have experience of working in ATIMPS (or CTIMPS where appropriate)

What we offer

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As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below: o 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) o Additional 5 days' annual leave purchase scheme o Defined benefit career average revalued earnings pension scheme (CARE) o Cycle to work scheme and season ticket loan o Immigration loan o Relocation scheme for certain posts o On-Site nursery o On-site gym o Enhanced maternity, paternity and adoption pay o Employee assistance programme: Staff Support Service o Discounted medical insurance Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

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As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/ If you have any queries regarding the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk quoting job reference