Job Description

Description

Salary Levels: c.68,000, c.85,000, c.99,000 (eventual offers will be based on benchmarked experience levels in combination with our selection criteria)

Location: Kings X, London; Tues - Thurs (3 days) at HQ, Monday + Friday, anywhere

Employment Type: Full-time

Contract: 3 years fixed-term (with the possibility for extension)

Closing Date: 24.08.25

About ARIA

ARIA is a new kind of R&D funding agency. We fund scientists and engineers to pursue research at the edge of the possible. From climate change to AI, society faces enormous challenges and opportunities that can be uniquely addressed by science and technology. ARIA was created to activate the UK's world-class R&D in new ways, so we can meet these head on.

We are growing our team to develop bold new approaches that can scale - from programmes to systems, processes and everything in between. If that sounds fun, come and build ARIA with us.

Learn more about how we work here.

Role Summary

As an ARIA Technical Specialist, you will have the rare chance to catalyse breakthroughs that could change the world. You'll sit alongside Programme Director Nathan Wolfe and their Programme Specialist on ARIA's Precision Mitochondria programme. You'll be exposed to every aspect of the programme's technical management from design through approval, project selection, and delivery.



We're looking for an adaptable team-oriented technical professional who's strongly motivated by the opportunity to catalyse a technological step change. You'll be working in a bold, talented & agile team, funding projects ('Creators') across the entire R&D ecosystem, from startups to universities, in the pursuit of groundbreaking advancements that will shape the future of science & technology.

Meet Nathan Wolfe

Nathan Wolfe is a member of ARIA's second cohort of Programme Directors. He is a biologist and scientific entrepreneur known for launching high-risk, high-impact initiatives at the intersection of life sciences, technology, and global health. He advises and invests in early stage technology companies and has worked with governments and philanthropic foundations on transformative science.

Nathan is leading an ARIA programme to make the mitochondrial genome programmable - developing a toolkit for reading, writing, and regulating mitochondrial DNA in vivo.

Find out more about what they're working on here. "We're not just looking for a mitochondrial expert--we're looking for a builder. If you want to be a part of a team shaping a critical new scientific capability from the ground up, we'd love to work with you."

Nathan Wolfe

, Programme Director

What you'll do

The scope of the role will evolve as ARIA continues to grow, but will broadly involve the following:

Technical Programme Advisory and Support

Act as the technical lead, with the Programme Director and their Programme Specialist, to shape and deliver a bold programme of research aimed at developing a toolkit for reading, writing, and regulating mitochondrial DNA in vivo. Review project proposals, grant applications, assess technical milestones, and stay close to the ground on what's being built and tested by Creator teams. Plan, lead, and contribute to technical discussions in project meetings, workshops, and formal reviews, bringing depth, challenge, and direction to every interaction. Provide evidence-based technical insight to the Programme Director and the ARIA team to support high-quality decisions and sharpen the programme's strategic direction. Confidently communicate complex scientific ideas surrounding the programme to stakeholders, from government and funders to key players across the ecosystem. Identify emerging trends and surface the most promising technologies, people, and ideas across the programme and its surrounding opportunity space. Co-author white papers, open calls, and technical reviews that articulate the ambition of the programme and set a clear, compelling vision for external communities. Work closely with the Programme Specialist and Creator teams to drive project delivery, tracking against ambitious technical milestones, benchmarking progress against the state of the art, and spotting opportunities for research cross-pollination to sustain momentum. Be the technical bridge between the PD and functional teams, ensuring execution aligns with the needs of the ecosystem's understanding of the programme.

Connecting the Programme to the Ecosystem

Represent the programme, often on behalf of the Programme Director, at events, workshops and talks. Build trusted relationships with world-class researchers, labs, and founders working at the forefront of the programme's focus area. Work closely with ARIA's Activation Partners to ensure Creator teams can access the right tools, platforms, and networks to accelerate translation and achieve impact beyond ARIA's direct reach.

Define and Cultivate ARIA's Technical Culture

Collaborate across ARIA on funding models, budgets, tooling, and operational mechanisms to support effective, flexible funding and programme delivery. Contribute as a member of ARIA's team of Technical Specialists ('T-Specs'), sharing best practices and learnings between programmes to strengthen ARIA's portfolio of work. Help build and sustain ARIA's scientific and operational culture.

Who you are

Essential Criteria

You have first-hand exposure to developing tools and methods in mitochondrial biology, of relevance to the technical areas in ARIA's Precision Mitochondria programme thesis. You have a strong understanding of mitochondrial biology with prior research in mtDNA, heteroplasmy or mitochondrial transfer. Familiarity with mitochondrial DNA structure & function, mitochondrial gene expression systems, membrane transport mechanisms (e.g. TIM/TOM), heteroplasmy dynamics, and organelle biology. Hands-on experience with experimental systems, ideally including cell-based or in vivo models. You excel in grasping and navigating diverse technical projects. You excel at translating complex technical concepts and timelines to diverse stakeholders, effectively bridging gaps between diverse teams and perspectives. You are willing to ask questions and can rapidly learn and adapt to new scientific areas, comprehending key components of new technical disciplines. You can uncover non-obvious opportunities and risks, connecting teams, ideas, and research threads in novel ways that drive adoption and translation. Highly adaptable, you are okay with uncertainty and a fast-paced environment.
You comprehend and articulate complex concepts clearly and with conviction, think and communicate with structure, and interrogate ideas effectively.

Desirable Criteria

Strong working knowledge of synthetic biology, nucleic acid delivery, or relevant measurement platforms. Well-connected in the mitochondrial biology community, with an understanding of emerging tools and players. You have worked in academia, biotech, or translational/start-up environments. You have successfully performed technical assignments that require unconventional or novel approaches. You are skilled in identifying technical bottlenecks, risk analysis and resolution, tracking technical milestones, and reporting on complex technical projects. You have a strong working knowledge of the UK R&D ecosystem.

Qualifications

You have a Scientific qualification, with a preference for PhD or other deeper technical experience, in mitochondrial biology.

Benefits

27 days annual leave provision, with the option to buy/sell additional days Hybrid working arrangements; 60% in office / 40% at home Supportive environment for learning and development opportunities Enhanced family leave arrangements A free and confidential 24/7 employee assistance programme 2 days of paid volunteer days 5% defined contribution pension scheme with Smart Pension Cycle to Work scheme An excellent office location in Kings X, London






Not sure you meet 100% of our criteria? Don't worry. If you believe that you could excel in this role, we encourage you to apply. We want to attract the broadest array of candidates, including those with diverse workplace experiences and backgrounds. Whether you're new to this, returning to work after a gap in employment, simply looking to transition, or taking the next step in your career path, we will be glad to have you on our radar.

Please use your cover letter to tell us about your interests and what you hope to bring to this role.



If you require any reasonable adjustments throughout the recruitment process, please notify us and we will make every effort to accommodate you. Disclosing any requests are intended to provide ARIA with the best opportunity to support candidates and will have no negative impact on your recruitment process.

Please note; You will be required, as and when necessary, to travel to different locations around the UK to support projects, depending on the Programme you are designated to.


ARIA adopts a highly considered approach to ethical and social responsibility. You can read our policy here

. Our research and development activity will abide by the 3Rs principle. You can read about those

here.

About ARIA