Job Description

Respiratory, Immunology and Inflammation Translational Unit (RIITU), within RIIRU therapy area is accountable for end-to-end disease area translational science to inform therapy area and program level biomarker strategies (from preclinical to launch) to increase the probability of success from preclinical to clinical transitions and enable earlier and higher confidence asset related decisions. This includes generation of foundational data as well as disease biomarker development and validation that allow timely deployment of tools/biomarkers to support Proof of Mechanism (PoM), signs of clinical efficacy, Proof of Concept (PoC), and pairing Mechanisms of Action (MoAs) with patient subtypes to predict responder populations.


We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.


We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.


Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

In this role you will

Lead and/or contribute to developing innovative translational strategies in Respiratory for assets ranging from preclinical to clinical stage of development. Develop biomarker strategies aligned with clinical development plans to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient stratification/selection. Represent RIITU at Early Development Team (EDT), Clinical Matrix Teams (CMT) and clinical trial study teams (ST). As part of the CMT and clinical ST, establish clear decision-making criteria to enable biomarker-informed clinical decisions. Provide input on biomarker-related elements of clinical study documentation for study start and reporting of biomarker data generated from clinical trials Provide scientific expertise and technical guidance to enable timely biomarker sample collection and analysis including from high dimensional assays to deliver high quality biomarker data packages to inform clinical development, integrated evidence plan and regulatory strategy. Collaborate with cross-functional teams include biology, translational disease teams, human genetics and genomics, clinical, medical affairs to ensure end-to-end biomarker data generation for asset needs and reverse translation to support the pipeline

Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

Ph.D. in a relevant scientific discipline e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field) Experience in translational science and biomarker development in a clinical trial setting within the pharmaceutical or biotechnology industry. Respiratory disease area knowledge and understanding in translational/biomarker development and implementation Experience of working in a clinical trial setting, working as part of a clinical study team and experience of authoring and oversight of clinical and regulatory documents Knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation. Experience in managing external collaborations with academic partners and CROs Strong interpersonal, matrix leadership and communication skills as well as ability to thrive in a matrix environment.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

Demonstrated scientific capability as evidenced by publications, research reports, and external presentations. Up to date knowledge and deep understanding of major molecular and genomic assay technologies and platforms Experience with novel technologies e.g., spatial transcriptomics and AIML

Closing Date for Applications - 19th of September 2025 (COB)

Please take a copy of the , as this will not be available post closure of the advert.


When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.


At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.


Find out more:


Our approach to R&D .

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.


People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.


GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.


We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.


Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.


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