Job Description

The Role:

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases.


As an employee, you'll be part of a continually growing organization, working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives.


Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience, with the potential to make a significant impact on patients' lives worldwide.


Moderna's mission is to establish a leading-edge research, development, and manufacturing facility at Harwell, as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic, NHS and government partners across the UK. We're looking for global experts eager to join us in this endeavour, contributing to a future where access to life-saving vaccines is a reality for all.


We are seeking a hands-on and technically adept GxP IT Systems Engineer to support Moderna's manufacturing operations at our Harwell site. This is a highly interactive role embedded in site operations, working alongside automation engineers, QC analysts, warehouse teams, and manufacturing operators. You will serve as the critical link between IT and Operational Technology (OT), delivering robust, compliant systems performance and exceptional end-user support.


This is a dynamic opportunity for an individual contributor who thrives in complex, regulated environments and enjoys maintaining the technical backbone that drives GMP production. With exposure to modern observability, cybersecurity tooling, and the potential to work closely with Generative AI and automation systems, this position places you at the forefront of digital manufacturing in biotechnology.

Here's What You'll Do:

Your key responsibilities will be:

Ensure compliance with GMP and data integrity standards, supporting inspections, audits, deviations, CAPAs, and SOP adherence. Provide Tier 1 support for manufacturing operations, responding to shop floor issues across workstations, HMIs, scanners, label printers, and Thin Clients. Triage and resolve IT incidents, requests, and change controls using a service-oriented mindset and SLAs. Manage infrastructure operations including troubleshooting of Windows servers, VMs (VMware/Hyper-V), Active Directory, DNS/DHCP, and time sync services. Support change execution activities in a validated GxP environment, maintaining audit trails and system states. Use observability tools such as Dynatrace, Splunk, and PagerDuty to monitor system health and resolve performance issues. Participate in endpoint protection and vulnerability management in coordination with security teams using tools like CrowdStrike. Maintain CMDB accuracy, system inventories, configuration baselines, and network documentation.

Your responsibilities will also include:

Provide day-to-day end-user IT support, including configuration and maintenance of laptops, mobile devices, and peripherals. Diagnose and resolve issues related to OS, Microsoft Office Suite, Outlook, and third-party applications. Maintain detailed documentation for tickets, repairs, imaging, data wiping, and asset tracking. Deliver a high-quality, customer-centric experience in all end-user interactions. Collaborate with QA, QC, Automation, Plant and Lab Engineering, and Digital Core teams to coordinate system downtime, restoration, and change advisory reviews. Participate in after-hours or weekend support activities as needed based on manufacturing demands.

The key Moderna Mindsets you'll need to succeed in the role:

"We behave like owners. The solutions we're building go beyond any job description."

In this role, taking ownership is vital -- you'll be the bridge between IT, automation, and the GMP shop floor, managing essential systems that directly impact product delivery. Your ability to act proactively and think holistically ensures production continuity and regulatory alignment.

"We digitize everywhere possible using the power of code to maximize our impact on patients."

As a GxP IT Systems Engineer, you'll operate in a highly digitized environment using advanced monitoring, cybersecurity, and infrastructure automation tools. Your contribution will enable faster, smarter, and safer operations that ultimately accelerate the delivery of mRNA medicines to patients.

Here's What You'll Bring to the Table:

Education and Experience

Bachelor's degree in computer science, Information Technology, Industrial Engineering, physical science or related field or relevant experience. Minimum of 3-5 years of experience supporting IT/OT systems in manufacturing and labs. Experience working in a BioPharma, GxP environment Some experience working with virtual environment (VMware/Hyper-V) and/or cloud platform (AWS preferred) Some experience working with RDBMS (SQL Server or Oracle) Some experience working with backup/recovery systems (Acronis, Veeam, N2WS, etc.) Some experience working with Cybersecurity endpoint protection applications (CrowdStrike, Symantec, McAfee, Carbon Black, etc.) Some experience working with infrastructure tools (Dynatrace, Pager Duty, Splunk) Excellent Windows and Microsoft Office Suite trouble shooting skills, as well as hardware trouble shooting skills. Experience with Apple device support for both MacOS and iOS, including the JAMF environment Experience with Service Now a plus Basic understanding of network routing, switching and firewall concepts.

Skills and Competencies:

Creative, analytical, and strong problem-solving skills. Ability to troubleshoot complex issues in a high pressure environment. Ability to react under pressure to any given situation that may arise, in a professional manner and with positive results, in support of a multi-location, 24x7 environment. Ability to work hard to effect change in a dynamic, high standards environment while maintaining a positive approach with management and peers. Highly collaborative work style. Strong interpersonal skills with the ability to build successful professional working relationships. Ability to work effectively in a cross-functional, fast-paced project environment.

At Moderna, we believe that when you feel your best, you can do your best work. That's why our global benefits and well-being resources are designed to support you--at work, at home, and everywhere in between.

Quality healthcare and insurance benefits Lifestyle Spending Accounts to create your own pathway to well-being Free premium access to fitness, nutrition, and mindfulness classes Family planning and adoption benefits Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investments Location-specific perks and extras!
The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.


By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.


We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.


As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.





If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.


Moderna is a smoke-free, alcohol-free, and drug-free work environment.


Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!


Moderna is committed to equal opportunity in employment and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.


We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.


Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at leavesandaccommodations@modernatx.com .


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