Job Description

Associate Scientist - Target Discovery | Biotech | CHO Cell Lines | CRISPR

Location:

Oxford

Salary:

34k - 37k + benefits


We're hiring an Associate Scientist to join an innovative biotech team focused on advancing mammalian cell line development. If you're experienced in CHO cell culture and CRISPR gene-editing, and you're passionate about target discovery, this could be your next move.

What you'll be doing:

Designing and executing CHO cell culture experiments using small-scale and high-throughput models Running CRISPR knockout screens and transfections for gene editing Applying molecular and cell biology assays (qRT-PCR, Western blotting, ELISA) Operating the BD FACSAria Fusion Flow Cytometer for single cell cloning and analysis Supporting cell line development using technologies like Beacon and Ambr15 Writing SOPs, maintaining lab documentation, and training junior scientists Ensuring lab safety standards and participating in out-of-hours cell culture as needed

What we're looking for:

BSc/MSc with 3+ years or PhD with 1+ years in a biotech or pharma environment Strong experience with CHO suspension cells, single-cell workflows, and genotyping Skilled in CRISPR/Cas9 techniques and FACS-based cell sorting Comfortable working independently and collaboratively in a fast-paced lab Experienced in experimental planning, troubleshooting, and scientific communication

Nice to have:

Familiarity with Beacon, Ambr15, or 96-well high-throughput models Experience working safely with lentiviral plasmid systems in a CAT2 environment Understanding of monoclonal antibody production and critical quality attributes (CQA)

Looking to play a key role in breakthrough biologics research? Apply now!