Job Description

MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU):

The MRC PPU is one of the world\'s most renowned centres for research on protein phosphorylation and ubiquitylation ( ). Many world-leading researchers in the field of signal transduction have trained within the MRC PPU. The major aims of the MRC PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease, to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation, to generate reagents and improve technologies. A key remit of the MRC PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research.

Division of Signal Transduction Unit (DSTT):

The Division of Signal Transduction Therapy (DSTT) was established in 1998. This division operates as a unique collaboration between scientists in the MRC PPU and signalling researchers at the University of Dundee\'s School of Life Sciences (Simon Arthur, Doreen Cantrell, Alessio Ciulli, Ron Hay, Angus Lamond, Henry McSorley, Ignacio Moraga, Adrian Saurin,) and three leading pharmaceutical companies (Boehringer Ingelheim, GlaxoSmithKline, Merck Serono). The DSTT is widely regarded as a model for how academia should interact with industry. The DSTT operates as a simple bridging mechanism to enable our PIs working on ubiquitylation and phosphorylation to effectively interact with three major pharmaceutical companies to help accelerate the early stages! of drug discovery.

Your priorities will include:

• Liaise with and support the Platform Lead Scientist to ensure the Proteomics Platform is run and maintained effectively to meet the needs of UK DRI researchers.
• Carry out studies on behalf of other researchers, applying your technical skills in bulk, single cell and/or imaging mass spectrometry and related techniques to enable the best experimental outcomes.
• Carry out analysis of data from mass spectrometry experiments and advise others on data analysis.

Who we\'re looking for:

• Masters or other post-graduate qualification in biological sciences or related subject area, or equivalent experience
• Experience of handling, purifying, and carrying out analysis on protein samples
• Experience with one or more aspects of mass spectrometry, including experimental design, sample preparation, running samples, data analysis
• Good interpersonal skills with an ability to work co-operatively in a multidisciplinary setting

IT proficiency at advanced user level (Spreadsheet, Word Processing, Database, Email, Web based applications)

The position will be funded for 3 years in the first instance, with a view for renewal

The position is full time

The diversity of our staff and students helps to make the University of Dundee one of the top universities in the UK. Family friendly policies, staff support networks for BME and LGBT staff, membership of Athena Swan and Stonewall, as well a full range of disability services, create an enjoyable and inclusive place to work.

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