Job Description

The Role

To help drive therapeutics discovery and characterisation we are seeking a candidate at Scientist level. They will have a key role in growing the phage display capability to derive antibody drug candidates for the pipeline. The role offers a great opportunity to learn about antibody discovery from an expert team and to develop technical expertise in the use of display technologies. This role will include day-to-day responsibility for general lab upkeep, equipment maintenance, maintaining reagent stocks and health and safety.

Responsibilities

Perform phage display selections to support drug discovery for future therapeutic projects Perform sequence analysis and screening experiments on antibodies derived from phage display selections to identify leads Maintain up to date knowledge in display technology and collaborate with fellow scientists in use of phage display As required, assist with other types of biochemical assays, protein expression and purification and biophysical analysis techniques, such as surface plasmon resonance, as part of the downstream discovery cascade Maintain laboratory equipment, reagent stocks, general lab cleanliness and smooth day-to-day running of the laboratory Perform all work demonstrating due care and attention to all health and safety and COSHH regulations, and Human Tissue Act records where required Maintain accurate and up-to-date laboratory notebook and electronic records Communicate efficiently, interpret and summarise data for presentation to different audiences

Experience and Requirements

BSc or MSc degree in a relevant scientific subject (or industry equivalent experience) Direct experience in phage or other display technology Attention to detail, ability to follow protocols, quick learner Hands on technical experience in performing diverse biochemical assays & techniques eg ELISA, immunoassays, magnetic enrichments, kinetic assays, homogenous assays Experience with molecular biology techniques eg PCR, cloning, sequence analysis An ability to work independently, developing, running and trouble-shooting new scientific techniques and experimental protocols An ambition to work with the Forth team to build a transformative company A team player who proactively and directly communicates and collaborates with other team members

The Company

Forth Therapeutics is an exciting new therapeutics company with R&D sites in Cambridge and Edinburgh. The company uses cutting edge spatial transcriptomics technology and proprietary 3D in vitro models to discover and validate novel targets for treatment of liver diseases. World-leading expert founders and an experienced management team are in place to rapidly deliver therapeutic drug candidates and extend the platform to bolster the pipeline for the future.