The post holder is a member of a multidisciplinary team developing the use of hepatocyte transplantation in children with liver-based metabolic disorders. They will be based at the Institute of Liver Studies laboratories within the Cheyne Wing at King's College Hospital.
The post holder shall work on research project which aims to explore the immunomodulatory and regenerative potential of MSCs, with the goal of developing advanced therapy medicinal products (ATMPs) for clinical translation.
1. Conduct independent research into the immunomodulatory effects and therapeutic mechanisms of MSCs in biliary atresia models.
2. Employ a range of cellular and molecular techniques, including flow cytometry, ELISA, and advanced microscopy.
3. Collaborate closely with other researchers within the Hepatocyte Biology and Transplantation Group and with clinical partners.
4. Present work at weekly research meetings and contribute to publications, grant applications, and conference presentations.
5. Support junior researchers and students, providing scientific advice and training where appropriate.
6. Participate in GMP-compliant cell isolation and processing where required
7. Engage with the broader scientific and clinical community through lectures, seminars, and journal clubs
The Trust provides a full range of local and specialist services across its five sites. The trust-wide strategy of Strong Roots, Global Reach is our Vision to be BOLD, Brilliant people, Outstanding care, Leaders in Research, Innovation and Education, Diversity, Equality and Inclusion at the heart of everything we do. By being person-centred, digitally-enabled, and focused on sustainability, we aim to take Team King's to another level.
We are at a pivotal point in our history and we require individuals who are ready to join a highly professional team and make a real, lasting difference to our patients and our people.
King's is committed to delivering Sustainable Healthcare for All via our Green Plan. In line with national Greener NHS ambitions, we have set net zero carbon targets of 2040 for our NHS Carbon Footprint and 2045 for our NHS Carbon Footprint Plus. Everyone's contribution is required in order to meet the goals set out in our Green Plan and we encourage all staff to work responsibly, minimising their contributions to the Trust's carbon emissions, waste and pollution wherever possible.
General
The post holder has a general duty of care for their own health, safety and wellbeing and that of work colleagues, visitors and patients within the hospital, in addition to any specific risk management or clinical governance accountabilities associated with this post.
To observe the rules, policies, procedures and standards of King's College Hospital NHS Foundation Trust together with all relevant statutory and professional obligations.
We want to be an organisation where everyone shares a commitment to delivering the very best care and feels like their contribution is valuable and valued.
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