Job Description

Posted:

21 November 2025

Senior Manager, Risk

------------------------


London
Full time
Finance
Permanent

Salary

:



Competitive

Benefits:

Competitive

Closing Date:

5 December 2025

Ref:

497

Job Title: Senior Manager, Risk

Location: London

Job Type: Permanent and hybrid.

This role requires 3 days in the London office, 2 days working from home.

Please note that we are only accepting applications until the 5

th

December, and we are particularly keen to see applications from individuals that can start in early 2026.

Agencies: We will only work with recruitment partners on our preferred supplier list and will not engage with speculative CVs submitted.



Are you passionate about making life science life changing and delivering impact for patients? We want to hear from you.

About the role:

We are currently looking to recruit a Senior Manager, Risk. The role oversees LifeArc's risk management and insurance, and provides support to the Internal Audit team, coordinating and tracking the agreed Internal Audit actions.

Success in this role means that you will:

Maintain a complete and effective risk management framework across the company Embed a culture of risk management across the organisation through effective business partnering Provide input to setting risk appetite Support an outsourced Internal Audit model to ensure successful implementation of the outsourced providers assurance program Manage the Insurance cover
Track the completion of Internal Audit actions

About you:

Responsibilities are to:

Ensure a robust and effective risk management system is in place which is aligned to the LifeArc strategy Partner with all functions to ensure that risk is managed at all levels of the organisation and is seen as an enabler to deliver LifeArc's strategy Provide input to Senior Management and Executive team highlighting progress, and areas of concern, with recommendations to drive corrective action Monitor the internal control environment at LifeArc to proactively identify gaps and areas of risk Work with functions to recommend improvements to controls where necessary Assist on new projects, including ensuring that adequate controls are put in place Support an outsourced internal audit model and work in partnership with the provider to help them develop and implement a fit for purpose, efficient and value adding assurance program. This will include maintaining an assurance universe, providing input to the audit plan and working with both internal stakeholders and the outsourced provider to enable high quality audits Work with functional areas to drive remediation of internal audit recommendations Manage business continuity planning across LifeArc ensuring the plan is current and fit for purpose including training, testing and stakeholder buy in Monitor LifeArc's insurance provision and lead the negotiation/renewal of insurance policies ensuring that the level and scope of cover is appropriate for LifeArc's needs for the following year Lead significant new projects as required Manage competing priorities whilst balancing needs of department, function and company Maintain own technical competence within role including strong understanding of both the internal and external landscape

Education & experience required:

Essential:

Successful track record and relevant experience in risk management Evidence of excellent relationship management and business partnering skills with key intermediaries Excellent analytical skills with the ability to think strategically and creatively Strong project management skills Enthusiastic advocate of risk management Ability to work independently with minimal direction Bachelor's Degree

Desirable:

Experience of a research function within the Pharma/Biotech/Life Science sector Recognisable professional qualification an advantage

Key competencies:

Integrity Flexibility Risk intelligence Influencing Business partnering Commercial awareness Good communication Analytical

About us:

LifeArc is a not-for-profit life science organisation, leading the way for change in rare diseases in the UK and supporting promising initiatives in global health. We seek out research in areas of unmet need that has great potential, providing support to help it become breakthroughs that change lives.

What we can offer you:

Focused on finding life changing solutions for underserved patients, our people thrive in an inclusive, and supportive environment that prioritises their health and wellbeing. Our multidisciplinary approach guarantees our people growth opportunities, while our culture of innovation and collaboration drives the impact we make delivering on our purpose of 'putting patients at the centre of everything we do'.


We are dedicated to creating a diverse, flexible, equitable and happy work environment so our colleagues can thrive as their truest selves. We act with courage, curiosity, care & commitment to deliver quality & excellence for our patients and each other Join us, and you'll be given the scope to develop your professional skills and experience in a safe, supportive and challenging environment


Salary will be determined by qualifications and experience along with other exceptional benefits. Because we understand everyone has different requirements, our flexible benefits allow you to choose those which are important to you. Our pension scheme offers employer contributions of up to 12%, private health insurance, and annual leave of 31 days PLUS bank holidays.


Don't meet every single requirement? Studies have shown that women and people from minority ethnic backgrounds, for example, are less likely to apply to jobs unless they meet every single qualification. At LifeArc we are dedicated to building a diverse, inclusive, and authentic workplace, so whatever your background or lived experience, if you're excited about this role but your experience doesn't align perfectly with every qualification in the job description, we encourage you to apply anyway. Our top priority is finding the best candidate, and you may be just right for this or other roles.


We all have potential. At LifeArc, you'll discover what you can really do with it.

Equal Opportunities

At LifeArc, we commit to advancing equal opportunities and building a diverse workforce by ensuring a fair, inclusive, and accessible recruitment experience for all. We employ individuals based on their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion, or belief. Our commitment to equity, diversity and inclusion includes creating a culture where everyone feels they belong, is valued for who they are and has the opportunity to translate their potential.


We want every candidate to do their very best. If you require special assistance or reasonable adjustments, please be sure to let us know in advance what will be most useful for you and / or to discuss your needs.


We only work with recruitment partners on our preferred supplier list, and will not engage with speculative CVs submitted.


Please note we are actively recruiting, and the closing date may be brought forward if we find the right person for this role.