Job Description

About the Role

We are looking to appoint an enthusiastic and experienced senior postdoctoral researcher to join Dr Sharma's Mechanistic T Cell Genomics group. The candidate will the lead on a project focusing on understanding signalling via inhibitory receptors in T cells using functional genomic screening approaches in primary T cells.

The post is funded via the Wellcome Trust and is available as a fixed-term contract for 3 years, with a possibility to extend. If you are interested in this position and have the skills and experience, we are looking for, please apply below. You will be required to upload a CV and supporting statement as part of your online application. Informal inquiries can be sent to Dr Sumana Sharma (sumana.sharma@rdm.ox.ac.uk).

Only applications submitted online and received before midday on Thursday 20th November 2025 will be considered. Interviews will be held as soon as possible thereafter.

About You

You should hold a PhD and postdoctoral research experience for this post. The ideal candidate will have expertise in functional genomic screening in primary T cells and the ability to establish high-throughput assays in T cells.

You should have a strong interest in T cell signalling pathways and demonstrate experience in integrating computational and experimental approaches to address key biological questions. Experience in supervising junior researchers and contributing to grant writing would be advantageous.

In this role, you will lead a project investigating the similarities and differences among inhibitory receptors in T cells, providing both strategic and hands-on leadership. You will also play a key role in shaping the future scientific direction of the group and supporting future grant development.

About the Radcliffe Department of Medicine

The Radcliffe Department of Medicine (RDM) within the Medical Sciences Division is one of the largest departments in the University of Oxford. RDM is a multi-disciplinary department which aims to tackle some of the world's biggest health challenges by integrating innovative basic biology with cutting edge clinical research.

Benefits of working

As an employer, we genuinely care about our employees' wellbeing and this is reflected in the range of benefits that we offer including:

An excellent contributory pension scheme

38 days annual leave

A comprehensive range of childcare services

Family leave schemes

Cycle loan scheme

Discounted bus travel and Season Ticket travel loans

Membership to a variety of social and sports clubs


See https://hr.admin.ox.ac.uk/staff-benefits for more information.

Application Process

"Committed to equality and valuing diversity"

The post is Full time and fixed-term for 3 years in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application. The supporting statement should include a cover letter and should also clearly describe how you meet each of the selection criteria listed in the job description. Click here for more information and advice on how to write an effective supporting statement.

Only applications received before 12:00 midday on 20/11/2025 will be considered.

Interviews are due to take place on early December