Job Description

Position: Business Operations Lead

Location: London, UK

Competitive Salary & Excellent Company Benefits

AstraZeneca is seeking an exceptional Business Operations Lead to design, inspire and implement the operations priorities aligning the overarching Oncology Business Excellence (OBEX) and Oncology Business Unit (OBU) strategy. Based in London, you will Lead the Business Operations team to identify and implement opportunities for the organisation to meet or exceed performance objectives, maximise potential of new asset launches, enhance our go-to-market design, and optimise the operations that enable and drive performance. You will Partner with cross-functional leaders to establish priorities for in-line and pipeline assets - linking strategic direction with operational execution, and also serve as a core member of the OBEX LT to build, inspire and implement business excellence strategies for the future.

What you'll do

Lead the team to deliver design, evolve and execute key business operations and lead the oncology business unit (OBU) to enhance the go-to-market model; setting direction and driving teams to leverage, and gain insight from, multi-channel customer engagement.


You will partner with OBEX leadership and cross functional teams, local and global, to identify opportunities for optimisation, automation & efficiencies across all OBU operations, as well as work with senior leaders, OBEX LT and cross functional teams to prepare the UK OBU for inline and pipeline performance.

Other Responsibilities will include:

People Leadership

Lead a team of high performing individuals to set and implement strategies to drive performance and achieve business outcomes Partner with OBEX and cross-functional leaders to identify priority areas for business transformation Represent business operations at OBEX LT, FLTs and, where appropriate, OLT & EUCAN LT Responsible for engaging with Global and European Regional Teams to leverage initiatives, resources and tools to support local initiatives Accountable for upskilling and continued development of Business Operations Team

Leader of Business Operations Team (40%)

Provides vision and effective leadership of the Business Operations team to direct, challenge, coach and support people and their activities Ensures the team is performance-focused, inclusive, building strong cross-functional collaborative relationships and delivering customer-centric solutions Cultivates matrix working within a team and across the business Provides career development support and guidance to team members. Manage allocated budget

Business Partner (30%)

Work with Heads of Franchise; Medical, Marketing, Sales and Access Leads and other relevant business leaders to establish organisational development priorities, map strategies to affect change, optimise processes to deliver on the ambitious goals Enhance GTM model and customer engagement channel use. Define and deliver engagement insights Responsible for engaging with Global and European Regional Teams to leverage initiatives, resources and tools to support local initiatives Works with OBEX Leadership Team to develop and deliver insights, enhance future fit organisational capabilities and improve performance Leverage, manage and inspire stakeholders throughout delivery

Driving Key Commercial Business Operations (30%)

Deliver OBU Incentive scheme design, reporting and processing. Ensure accurate and timely payouts of FF incentive payments Overall accountability for direct leadership of the evolution and implementation of Key Account Management Process and Framework Provide commercial effectiveness insights (promotional and non-promotional) to inform strategic design of segmentation and targeting across brand and field targets. Operationalise S&T through all relevant systems accurately and within agreed timelines Lead team to manage key strategic plan processes including but not limited to strategic plans, operational plans, launch planning

Essential Requirements

Strategic & Commercial Expertise

Strategic vision-setting and high-level conceptual thinking Deep understanding of core commercial processes (e.g., Incentive Design, Segmentation, Targeting, commercial analytics, channel effectiveness etc) Expertise in Go-To-Market (GTM) strategy design and channel implementation Strong knowledge and experience in Launch Excellence & Operations Broad understanding of disease areas and commercial models in the pharmaceutical sector (Oncology Desirable)

Operational Excellence

Expertise in key business operations management - technical and strategic Automation, optimisation and process design & implementation

Leadership & Project Management

Strong proven record of direct and indirect leadership and organisational skills Proven ability to prioritise, lead through complexity, and deliver under pressure Adaptive project management capabilities

Communication & Influence

Executive-level communication skills (written and verbal) Ability to influence and engage senior stakeholders across functions, geographies, and cultures Skilled in conflict management and resolution

Interested? Apply now!


Closing Date for Applications: COB 7th November 2025