Job Description

Ref Number

B02-09569

Professional Expertise

Laboratory Technical and Lab Support

Department

School of Life & Medical Sciences (B02)

Location

London

Working Pattern

Full time

Salary

See advert text

Contract Type

Fixed-term

Working Type

On site

Available for Secondment

No

Closing Date

09-Nov-2025

About us

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The Department of Neurodegenerative Disease is recognised as internationally leading in the study of neurodegenerative diseases causing dementia and related disorders. The Department has a strong focus on mechanistic dissection of genetic, molecular cellular and neuropathological processes which underlie neurodegeneration in particular diseases and across the neurodegeneration spectrum.



The mission of the Genetic Therapy Accelerator Lab, based in the Department, is to embed translational research into the basic research and clinical activities of the UCL Queen Square Institute of Neurology (ION). Its remit is to pursue discovery of novel therapies using RNA and AAV technologies, with identification and refinement of target for therapeutic intervention.



Combining laboratory and clinical expertise we focus on neuromuscular and neurological disorders, their mechanisms of disease, and cutting-edge RNA and AAV gene therapy expertise, by fostering cross-institutional collaborations, and facilitating RNA and gene therapy programs.

About the role

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We are recruiting a Research Technician to support a cutting-edge project into molecular mechanisms behind SCA29 and Gillespie Syndrome, which are congenital ataxia syndromes caused by mutations in ITPR1. The overall goals are to functionally validate mutations found in patients and investigate possible genetic and small-molecule therapies for these disorders in cellular models. You will be expected to learn many different and new techniques throughout this project and to perform them independently and with minimal supervision.



The post is available immediately and is funded by a philanthropic donation until 31 August 2028 in the first instance.



If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team (ion.hradmin@ucl.ac.uk).



For informal enquiries about the role please contact Dr Joanne Ng (j.ng@ucl.ac.uk).



A full job description and person specification for this role can be accessed below. To apply, please complete the online application form, and use the supporting statement section or upload a cover letter to outline how you meet the essential and desirable criteria for the role. Please do not upload any additional attachments as these will not be considered by the selection panel.

About you

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You will have a BSc in a relevant discipline (e.g., biomedical research), and experience with molecular biology techniques, with mammalian cell culture, and with molecular cloning, plasmids and/or competent bacteria. You'll also have excellent communication, collaboration, and problem-solving skills. An interest in neurological diseases, translational research and gene therapy, and experience of working in a team of academic and technical scientists is desirable.



This role does not meet the eligibility requirements for a Skilled Worker Visa certificate of sponsorship under UK Visas and Immigration legislation. Therefore, UCL will not be able to sponsor individuals who require right to work in the UK to carry out this role.

What we offer

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Starting salary offered on UCL Grade 6 at 36,433 per annum, inclusive of London Allowance.



As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:


41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) Additional 5 days' annual leave purchase scheme Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan Immigration loan On-site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance

Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.



We will consider applications to work on a part-time, flexible, and job share basis wherever possible.



This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information.

Our commitment to Equality, Diversity and Inclusion

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The Institute prides itself on operating in an all-inclusive environment irrespective of personal, physical, or social characteristics. Teamwork is highly valued, individual strengths are recognised and celebrated, and we are committed to advancing the careers of everyone. 12% of Institute staff are actively working on Equality, Diversity and Inclusion (EDI) initiatives; visit our EDI website for more information about our initiatives and priorities. The Institute also holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.


As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.


We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce; these include people from Black, Asian and ethnic minority backgrounds, disabled people, LGBTQI+ and gender diverse people in all roles, and women in Grade 9 and 10 roles.