Job Description

Job Title: Scientist (Renal Bioscience, Early CVRM) - Full time, Onsite
Location: Cambridge, UK
Introduction to the Role:
In Renal Bioscience, we discover novel medicines for kidney disease. We seek a well-organized, highly productive bench scientist who can independently design and execute experiments and effectively analyze, interpret, and present data.
As a Scientist in Early CVRM Renal at AstraZeneca, you'll join a vibrant team advancing new treatment options for renal disease. In the in vitro group, you will develop and deploy cellular models to drive targets and projects, collaborating with experts across functions and supporting project teams.
Accountabilities:

• Generate decision-enabling data to advance renal programs from target validation through lead optimization, directly contributing to AZ's mission to transform CKD outcomes.
• Plan and execute studies independently while collaborating in cross-functional teams.
• Elucidate mechanism of action via pathway modulation, target engagement, and biomarker readouts relevant to renal injury.
• Design studies with appropriate controls, replication, and statistics; ensure data integrity, traceability, and compliance with ELN and SOPs.
• Communicate findings clearly in internal and external forums.
• Be proactive, detail-oriented, and accountable; prioritize in a fast-paced environment and contribute constructively to team decisions.

Essential Skills/Experience:

• BSc or equivalent experience in biological sciences (e.g., bioscience, pharmacology, physiology).
• 2+ years hands-on human cell culture in 2D/3D systems, including assay development and troubleshooting.
• Proficiency in qPCR, Western blot, and fluorescence imaging with evidence of high-quality, reproducible data.
• Experience planning experiments, maintaining ELNs, and performing basic statistical analyses.
• Experience in pharma/biotech or translational academic labs.

Desirable Skills/Experience:

• Understanding of renal physiology and pathophysiology

Why AstraZeneca?
Here, curious minds come together in an inclusive environment where every voice can shape the science and the strategy. You will work shoulder-to-shoulder with bench biologists, data scientists, clinicians, and external collaborators to unlock new insights, fuse data with experimentation, and push boundaries in disease biology. With the tools, resources, and pace of a leading research engine, you will learn continuously, take smart risks, and see your ideas move from lab benches to studies that change patients' live
Next Steps:
Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.
Please apply via the link and one of our team will be in touch ASAP. This is being actively recruited so early application is advised.
Where can you find more?
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Date Posted 12-Feb-2026
Closing Date 26-Feb-2026
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Skills Required