Job Description

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.
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Senior Principal Statistician
You will work within a team applying your statistical expertise and innovative methodology to support clinical development within the Oncology pipeline. You will work closely with cross-functional teams to design studies from early first-in human trials to late-phase drug development. Our team is committed to utilising novel clinical trial designs and innovative statistical methods, including Bayesian techniques, to assess risk as well as probability of success for both studies and overall programs to enable informed decision-making.
Responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Provide statistical support to Project Statisticians and support studies across Oncology pipeline
• Contribute to statistical design and analysis of clinical trials across development phases using a wide range of statistical approaches (e.g. Bayesian methodology)
• Use simulations and advanced statistical methodology to inform trial design and risk assessment.- Develop and review statistical analysis plans, protocols and sample size calculations to support oncology clinical trials.
• Work closely with study teams (programmers, data managers and clinical colleagues) in support of clinical trials.
• Apply standard processes to tasks to ensure that deliverables are accurate, high quality and meet agreed timelines

Why You?
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals

• Master's degree or higher in Statistics, Biostatistics, Applied Mathematics, Mathematics, or a related quantitative discipline.
• Demonstrated relevant industry experience.
• Practical experience in statistical programming (R, Python) and model implementation.
• Hands-on experience with simulation methods and study design for oncology clinical development.
• Strong written and verbal communication skills for technical and non-technical audiences.
• Proven ability to work in cross-functional teams and to manage multiple priorities.

Preferred Qualification
If you have the following characteristics, it would be a plus

• PhD in Statistics or closely related field
• Experience with Bayesian methods, advanced predictive modelling, or causal inference.
• Track record of methodological innovation or contributions to publications

Closing Date for Applications - 4th March 2026
Please take a copy of the , as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.
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Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.
We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
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